Welcome to nodalpoint rebooted as a podcast (if you don’t care about the ‘why’, just scroll to the end and hit play). I started nodalpoint when I was a graduate student about 10 years ago and it evolved into one of the early bioinformatics/science blogging networks. For a bit more on the history of nodalpoint, please see this post. The site was active until at least last year, but as I moved on in my science career (mainly in industry), I found less and less time to maintain nodalpoint. There were some great contributions by Duncan Hull towards then end, however without a driver people ended up drifting off to do independent blogs. Although I had less time for nodalpoint, I was still following the conversation on blogs, Friendfeed, and now Twitter. I still wanted a way to contribute, but something a little more low-key and independent; with less requirement for frequent updates.
I have always been fascinated with radio, and the natural extension of radio for the Internet is of course podcasting. At the moment I have a train journey to work, which is the perfect time to listen to podcasts. With the notable exceptions of Deepak and Hari’s Coast to Coast Bio Podcast, I could not find any science podcasts relevant to me as a computational biologist. Of course there are plenty of podcasts in the style of what-kind-of-wacky-stuff-has-science-discovered-this-week, and some slightly better general science podcasts from Nature, Science and Futures in Biotech. And so it finally came together: a niche, the desire to reboot nodalpoint, and the expectation for updates on most podcasts not as frequent as blogs, delusions of radio grandeur etc.
I grabbed a mic, fired-up an audio editor, and then proceed to fall straight into a technology rabbit hole; of course I had to do it all on Linux which added an extra level of difficulty. I won’t cover the nuances of professional sound editing and broadcasting, suffice it to say that it is easy to podcast, very hard to do it well. Surprisingly hard. Of course that rich radio sound is only a small part of the equation: content, delivery, and a suitable guest are what really matter. I managed to convince Neil Saunders to be part of this amateur broadcasting indulgence of mine. Neil was a significant early contributor to nodalpoint and now has his own blog: What You’re Doing is Rather Desperate. So with a deep breath and production values be damned, I give you Nodalpoint Conversations Episode 01.
Part 1
- NoSQL and Cloud computing
Interlued 1
- Man or Astro-man ? (Track 12: Theoretical Sounds of Slow Motion)
Part 2
- What technologies interest you: metagenomics
- Pipelines and workflow tools
- Exploratory data analysis vs. workflow environments
- Bio* tool kits
- Your day-to-day work tools: ubuntu, ruby
- Programing language discussion, why ruby ?
- Monitoring the conversation: Blogs, Twitter and Friendfeed, a distraction ?
Interlude 2
- Reflections on how we work as computational biologists
Part 3
- Can open science work in the same way open source does
- Ratio of users to contributors to open source projects is large
- Why contribute ? Outreach is just a good thing.
- The mad sci-network
- Awareness, of open source, open science in the workplace.
- Awareness, but no uptake. Reference management apears to be the issue.
- Being cautious when making scientific claims
Wrap-up
- Thoughts on the future of nodalpoint conversations
Podcast: Play in new window | Download


This is wonderful. More podcasts the merrier and what a way to start. Of course, you could have chosen a guest who actually exists
I hope you do a better job of consistently churning out episodes than those c2cbio guys. Can’t wait for episode 2
| September 21, 2010 @ 1:29 pm
It’s early days, I’ll have to see how much momentum this has. I will definitely be trying for episode 2 in the next month. Podcasting is a very different beast when compared to running a weblog. For example, I listent to a lot of podcasts including c2cbio (looking forward to future episodes too!) but don’t engage in the same way that I do with Twitter/Friendfeed/comments etc. I suspect it is the passive nature of the medium.
| September 22, 2010 @ 9:23 am
Great to see nodalpoint back on the road again… is that *really* Neil Saunders?
| September 22, 2010 @ 4:53 pm
Cool idea!! hail to the Nodal Point!! Nodalpoint forever!!
| September 28, 2010 @ 2:25 pm
Looking forward to future episodes as well!!
| October 6, 2010 @ 5:15 pm
I think you did a fair job. I’ll donate if you make a couple more episodes. I’d love to have a regular Bioinformatics webcast to listen to. I’m fairly new to the field and don’t have enough time to keep up with the field in general much less master all the techniques and concepts I’ll be using.
Kudos on the start of something great.
| October 28, 2010 @ 4:25 am
Thanks for the positive comments, any kind of feed back is appreciated. I’m currently putting together an episode on Systems/Synthetic biology. Unfortunately I just don’t have much time to spend on this, so given the logistics and availability of guests it’s looking like the next episode will be released at the end of November.
And as far as donations go, you’re correct, it’s obviously too early for that. I liked the idea of using Flattr, but the way they have set it up is a little odd. To join the system is only a couple of Euro, but finding and flattring content is difficult without critical mass. And if you don’t use the balance in your account it doesn’t roll over to the next month, they take the remainder and donate it to charity. In which case you have to top up your account to start Flattring again.
I’m also considering re-branding as The nodalpoint podcast, rather than conversations. More flexibility.
| October 28, 2010 @ 12:24 pm
Awesome , this is really great. Enjoyed listening to it . The sound and quality is phenomenal. Looking forward to many more episodes
| January 3, 2011 @ 2:28 am
Thanks for listening. I do spend a lot of time fussing about sound quality, so I’m glad that’s noticeable. The next episode is almost done, it explores systems biology and includes an interview with Pedro Beltrao.
| January 3, 2011 @ 3:38 am