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WHY DO PROTIENS HAVE UNWANTED RESIDUES IN THEIR SEQUENCE?

Thu, 2005-09-15 20:10 — chimera

Isoenzymes have similar function but different
structures.
             
This means these protiens have similar active sites. We know that some enzymes
even if their polypeptide chain is shortened can perform their function.
So what's the Use of these "unwanted" amino acids?
                             
Please make me Knowledgable in this scientific query.


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Mon, 2005-09-19 10:23 — chris

Structure vs function

Like the perl folks say, there's more than one way to do it. You've asked a highly context-dependent question: the answers are likely to be different for each protein.

Two uses I can think of for the extra amino acids : (i) responsible for some other function/interaction; (ii) loop material, allowing the polypeptide to bend into its active conformation more easily.


Fri, 2005-09-16 00:07 — Greg

You have asked an

You have asked an interesting question. However if you want this posted to the front page I would suggest adding some links to papers or articles that discuss this question. Or maybe you could give a brief introduction with some real examples ?

See the posting guide for more suggestions and only your hard work can make you knowledgeable about science :)