The SciView project is back with another interview. This time, Dr Jeremy Squire answered my questions. He is cytogeneticist from the Ontario Cancer Institute, so I tried to get his view on some bioinformatics topics as wet lab scientist. Some great advices and opinions in his answers, not only for bioinformaticians.
http://blindscientist.genedrift.org/2007/06/25/sciview-part-3-interview-...
This is an announcement of a bioinformatics tool, published as freeware for the community.
Geneious is an easy-to-use, cross-platform (Windows, OS X, Unix) bioinformatics data analysis and visualization tool. It has an open API for writing plugins. You can use Geneious to compare genes from different species, to build an evolutionary tree to see how closely related they are, or to search for literature on any topic in medicine or biology. You can view and extract gene annotations from whole genomes, and interactive 3D graphics allow you to move around protein structures.
Version 1.0 of Geneious has just been published as freeware. Biomatters hopes that you will put the program to good use in your research, and we are eager to hear your comments and feedback.
Two of my favourite things and the subject of a 3-article feature in Nature this week, presumably for the festive season. The first of these is a fascinating look at the evolution of ADH genes.
Maybe I'm a little slow, but I've just come across iHOP (Information hyperlinked over proteins). I've only looked at the text spew, but I love it already. Azucar!
I was intrigued by the headline - Scientists decipher 21,000 genes. It's often hard to know what's been done from such headlines - decipher? Sequence? Analyse?
Anyways, turns out that the Japan Biological Information Research Centre (great name!) have produced an integrated database for 21 037 cDNA clusters with a very wide ranging annotation. It's well worth a look, though I got "server busy" several times. They also have this stupid front page which redirects you after 15 seconds for no apparent reason.
here is an enthusiastic biotechnolgist trying to make a mark in the field of genomics
Genomeweb Birney Announces Winners of Wager on Number of Human Genes - "GeneSweep, a friendly wager in which participants bet on the number of genes on the human genome, is officially over, and there are three winners -- although genome scientists have not definitively agreed on a number of genes in the human genome." "Birney said that there were 24,500 genes in the latest Ensembl build, human build 33. But he stopped short of saying that this number represents any final tally on the number of human genes. "We are confident we have about 21,000 genes in the human [Snowdeal: Bioinformatics]
A letter in the Lancet outlines a scenario in which the SARS virus could have come from the outer regions of our atmosphere. Interesting, and reasonably plausible arguments.
Upon hearing that he was awarded the Nobel Prize with Brenner and Horvitz, Sir John Sulston is quoted as saying that; "The worm [C. elegans] worked so well because the community held an ethos of sharing - just as the public genome projects have - from the beginning. We gave all our results to others as soon as we had them. From sharing, discovery
is accelerated in the community. Research is hastened when people share results freely." (The Guardian, October 8, 2002)
